Heterocyclic and benzoheterocyclic polyamides structurally related to the natural antibiotic distamycin A for the treatment of β-thalassaemia

US7396851B2 · kind B2 · utility

Assignees

• UNIVERSITA' DEGLI STUDI DI FERRARA · IT
• Associazione Veneta per la Lotta Alla Talassemia · IT
• Associazione per La Lotta Alla Talassemia Di Ferrara · IT

Inventors

• Pier Giovanni Baraldi · Ferrara, IT
• Nicoletta Bianchi · Mezzogoro, IT
• Giordana Feriotto · Ferrara, IT
• Roberto Gambari · Bologna, IT
• Carlo Mischiati · Rovigo, IT
• Romeo Romagnoli · Ferrara, IT

Key dates

• Filing date: Jul 1, 2002
• Grant date: Jul 8, 2008
• Expiry date: Mar 20, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P7/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of structural analogues of distamycin having the general formula (I), (II), (III), (IV) or (V) or their pharmaceutically acceptable salts, for the preparation of a medicament for the therapeutic treatment of β-thalassaemia.