Charge reversal of polyion complexes
US7396919B1 · kind B1 · utility
2Cited by
10References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1999 |
| Grant date | Jul 8, 2008 |
| Priority date | — |
| Expiry date | Jun 9, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An ionic polymer is utilized in “recharging” (another layer having a different charge) a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The resulting recharged complex can be formed with an appropriate amount of positive or negative charge such that the resulting complex has the desired net charge.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.