Regulation of hypoxia-inducible gene expression with antisense Inhibitory PAS domain protein
US7396922B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Nov 28, 2002 |
| Grant date | Jul 8, 2008 |
| Priority date | — |
| Expiry date | Apr 30, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A pharmaceutical composition comprises the sequence of SEQ ID NO:s 3-5 or pharmaceutically equivalent sequences. Methods employing the pharmaceutical compositions include treatments to increase angiogenesis, to stimulate HIF-1α function, to treat hypoxia-related conditions, and to maintain normal cell functions under hypoxia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.