Process for preparing symmetrical and unsymmetrical N,N-dihydrocarbylhydroxylamines

US7396959B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Gunter Scherhag · Heidelberg, DE
• Lars Wittenbecher · Mannheim, DE

Key dates

• Filing date: Dec 1, 2006
• Grant date: Jul 8, 2008
• Expiry date: Dec 1, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for preparing N,N-dihydrocarbylhydroxylamines of the general formula (I)where R1, R2, R3 and R4 are selected independently from among hydrogen, aliphatic, cycloaliphatic, heteroaromatic and aromatic radicals, or R1 and R2 and/or R3 and R4 are joined to form a ring, and not more than one radical among R1, R2, R3 and R4 is hydrogen, which comprises the steps a) reaction of hydroxylamine H2NOH or a salt of hydroxylamine with a compound of the general formula (II) or (III)where R1, R2, R3 and R4 are as defined in formula (I), b) hydrogenation of the compound formed in step a) in the presence of a catalyst, c) further reaction of the compound formed in step b) with a compound of the general formula (II) or (III) and hydrogenation of the reaction mixture in the presence of a catalyst and d), if appropriate, reaction of the salt of the dihydrocarbylhydroxylamine formed in step c) with a base.