Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof
US7399858B2 · kind B2 · utility
4Cited by
16References
20Claims
0Family size
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Key dates
| Filing date | Mar 7, 2006 |
| Grant date | Jul 15, 2008 |
| Priority date | — |
| Expiry date | Oct 14, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D489/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the catalytic production of hydrocodone derivatives and hydromorphone derivatives, respectively, utilizing a transition metal catalyst of the formula [M(PR4R5R6)nXm]p; wherein M is a Group VIII transition metal; R4, R5 and R6 are selected from the group consisting of alkyl, aryl, alkoxyl, phenoxy and combinations thereof; X is a halide or an anion; n is 1, 2, 3 or 4; m is 1 or 2; and p is at least 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.