Mutated gene coding for a lat protein and the biological applications thereof
US7399901B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Feb 14, 2003 |
| Grant date | Jul 15, 2008 |
| Priority date | — |
| Expiry date | Jul 13, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a mutated gene coding for a mutant LAT protein leading to exaggerated TH2 differentiation. The invention relates to biological structures containing the mutant, particularly non-human LAT gene, mutated animals, plasmids, chromosomal DNAs, embryos comprising the mutated gene, and applications thereof. The invention further relates to screening methods for drugs useful for treatment against asthma and allergy. Otherwise, the invention relates to methods for producing IgE antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.