Recombinant methods and materials for producing epothilone and epothilone derivatives
US7402421B2 · kind B2 · utility
2Cited by
27References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 2004 |
| Grant date | Jul 22, 2008 |
| Priority date | — |
| Expiry date | Dec 20, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/181
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells for the production of epothilones, epothilone derivatives, and polyketides that are useful as cancer chemotherapeutics, fungicides, and immunosuppressants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.