Compositions and methods for inhibiting abnormal cell growth
US7402561B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2005 |
| Grant date | Jul 22, 2008 |
| Priority date | — |
| Expiry date | Mar 9, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In the US about ⅓ of college women show evidence of HPV infection. The clinical problem may be even larger in developing countries. There are currently no effective therapies for HPV infections, aside from therapeutic cone biopsies, which often are followed by recurrent, progressive lesions. Thus, pharmaceutical compositions and processes for treatment of an HPV infection are detailed. In particular, a pharmaceutical composition for inhibiting growth of a human papilloma virus-infected cell is provided which includes a peptide halomethyl ketone inhibitor of a chymotrypsin or chymotrypsin-like protease and a pharmaceutically acceptable carrier. A preferred inhibitor is AAPFcmk.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.