Peptide inhibitor of TGF-β growth factors
US7402566B2 · kind B2 · utility
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Key dates
| Filing date | Sep 17, 2004 |
| Grant date | Jul 22, 2008 |
| Priority date | — |
| Expiry date | Jun 4, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/858
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A potent peptide inhibitor (SuperSog) of TGF-β family growth factor signaling, peptide variants thereof and nucleotide coding sequences therefore are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.