Antisense composition and method for treating cancer
US7402574B2 · kind B2 · utility
126Cited by
12References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 2005 |
| Grant date | Jul 22, 2008 |
| Priority date | — |
| Expiry date | Dec 13, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3233
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method and composition for treating colorectal cancer is disclosed. The method involves administering to a subject, a therapeutically effective amount of a morpholino antisense compound (i) having a nuclease-resistant backbone, (ii) capable of uptake by target cancer cells in the subject, (iii) containing between 10-40 nucleotide bases, and (iv) having a base sequence effective to hybridize to a region of processed or preprocessed human SNAIL RNA transcript.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.