System and method for cross-talk cancellation in a multilane fluorescence detector
US7402817B2 · kind B2 · utility
6Cited by
3References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 25, 2007 |
| Grant date | Jul 22, 2008 |
| Priority date | — |
| Expiry date | Jan 25, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6421
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed to a system and method for cross-talk cancellation for multi-lane fluorescence detectors. The invention may be implemented in accordance with a variety of systems, including systems for multi-capillary electrophoresis. The present invention is based on a special calibration procedure for determination of a channel cross-talk matrix and enables an accurate separation of the fluorescence emitted from individual capillary lanes. The proposed method for cross-talk calibration and removal is very useful for design and development of multi-lane single photon counting detection systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.