Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof
US7405215B2 · kind B2 · utility
13Cited by
5References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2005 |
| Grant date | Jul 29, 2008 |
| Priority date | — |
| Expiry date | Jan 31, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.