Bicyclic modulators of androgen receptor function

US7405234B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Chong-Qing Sun · Plainsboro, US
• Lawrence G. Hamann · North Grafton, US
• David J. Augeri · Princeton, US
• Yingzhi Bi · Plainsboro, US
• Jeffrey A. Robl · Newtown, US
• Yan Huang · Cambridge, US
• Tammy C. Wang · Lawrenceville, US
• Alexandra Holubec · Yardley, US
• Ligaya Simpkins · Titusville, US
• James Sutton · Princeton Junction, US
• James J. Li · Pennington, US

Key dates

• Filing date: Feb 17, 2004
• Grant date: Jul 29, 2008
• Expiry date: Nov 24, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides compounds according to formula I Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention.