V-like domain binding molecules and polynucleotides encoding therefor
US7405288B2 · kind B2 · utility
3Cited by
13References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 2006 |
| Grant date | Jul 29, 2008 |
| Priority date | — |
| Expiry date | Oct 27, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.