Process for making risperidone and intermediates therefor
US7405298B2 · kind B2 · utility
0Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 2003 |
| Grant date | Jul 29, 2008 |
| Priority date | — |
| Expiry date | Jan 21, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The formation of risperidone is enhanced by the use of enriched Z-isomer oxime intermediate(s) of formula (3) or (7).The oxime(s) can be isomerically enriched by a variety of techniques including the use of the novel acetic acid salt thereof, which affords, inter alia, resolution of the isomers and/or by heat conversion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.