Pyrrole-2, 5dione derivatives and their used as GSK-3 inhibitors

US7405305B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Pamela Albaugh · Carmel, US
• Jochen Ammenn · Hamburg, DE
• Timothy Paul Burkholder · Carmel, US
• Joshua Clayton · Oakville, CA
• Scott Eugene Conner · Elizabethtown, US
• Brian Eugene Cunningham · Martinsville, US
• Thomas Albert Engler · Indianapolis, US
• Kelly Wayne Furness · Avon, US
• James Robert Henry · Indianapolis, US
• Sushant Malhotra · South San Francisco, US
• Mark J. Tebbe · Hamburg, DE
• Guoxin Zhu · Noblesville, US
• Yihong Li · Millbrae, US
• Brian Raymond Berridge · Greenfield, US
• Charles Edward Ruegg · Indianapolis, US
• John Morris Sullivan · Greenfield, US

Key dates

• Filing date: Mar 5, 2003
• Grant date: Jul 29, 2008
• Expiry date: Jun 17, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides kinase inhibitors of Formula (I)