Method of screening remedy for heart disease and medicinal composition for treating heart disease
US7407767B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 15, 2004 |
| Grant date | Aug 5, 2008 |
| Priority date | — |
| Expiry date | Apr 15, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/325
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for screening a substance that inhibits the onset of anti-cardiac troponin I autoantibody-related disease, a pharmaceutical composition and a base material for therapy of cardiac disease that contains the substance obtained by aforesaid method thereof, a therapeutic apparatus that removes anti-troponin I autoantibody for aforesaid antibody related disease, a method of making an animal model for evaluating cardiac disease characterized by administrating anti-cardiac troponin I antibody, a method of selection of a therapeutic substance for cardiac disease characterized by using aforesaid animals, and a diagnosis of dilated cardiomyopathy characterized by measuring anti-cardiac troponin I autoantibody. An apparatus of the present invention that removes anti-cardiac troponin I antibody and a pharmaceutical composition for therapy of the antibody related disease may be useful for a therapy and/or prevention of cardiac disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.