Heterocyclic analogs of diphenylethylene compounds
US7407978B2 · kind B2 · utility
0Cited by
76References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 8, 2002 |
| Grant date | Aug 5, 2008 |
| Priority date | — |
| Expiry date | Jul 25, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.