System and method for scoring peptide matches
US7409296B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2003 |
| Grant date | Aug 5, 2008 |
| Priority date | — |
| Expiry date | Aug 6, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a system and method for scoring peptide matches. Embodiments of the present invention improves identification of peptides and proteins by introducing an appropriate signal detection based scoring system and what is believed to be the new concept of an extended match. To score a match between a first peptide and a second peptide, a stochastic model may be generated based on one or more match characteristics associated with the first peptide, the second peptide and their fragments. A first probability that the first peptide matches the second peptide, and second probability that the first peptide does not match the second peptide, may be calculated based on the stochastic model. And a match between the first peptide and the second peptide may be scored based at least in part on a ratio between the first probability and the second probability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.