Anti-cancer compounds
US7410656B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 22, 2004 |
| Grant date | Aug 12, 2008 |
| Priority date | — |
| Expiry date | May 26, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, andpharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.