Fusion polypeptides of human serum albumin and a therapeutically active polypeptide

US7410779B2 · kind B2 · utility

Assignee

• Novozymes Biopharma UK Limited · GB

Inventors

• Reinhard Fleer · Les Ulis, FR
• Alain Fournier · ᐙᔂᓂᐲ Waswanipi, CA
• Jean-Dominique Guitton · Paris, FR
• Gerard Jung · Montlhéry, FR
• Patrice Yeh · Paris, FR

Key dates

• Filing date: Jan 12, 2006
• Grant date: Aug 12, 2008
• Expiry date: Apr 29, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention includes biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for the preparation of such fusion polypeptides, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing such fusion polypeptides.