Patent · US Expired

Meningeal-derived stem cells

US7410797B2 · kind B2 · utility

3Cited by
5References
21Claims
0Family size

Inventors

Key dates

Filing dateJun 10, 2003
Grant dateAug 12, 2008
Priority date—
Expiry dateJun 10, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/90
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Stem cell lines derived from meningeal tissue such as dura mater, pia mater, or arachnoid mater, are disclosed. In various embodiments, the stem cell lines include greater than 80%, greater than 90%, or greater than 99% of pluripotent meningeal-derived stem cells. In other embodiments, the stem cell lines are induced to form nerve cells, bone cells, cartilage cells, Schwann cells, adipocytes, fibroblasts, or melanocytes with various inducing agents, such as antioxidants, steroid hormones, laminin, or various growth factors. Derivation of the current stem cell lines is accomplished through explantation or enzymatic dissociation of meningeal tissue, followed by expansion to large populations using growth media.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.