Method of synthesizing polynucleotides using ionic liquids
US7411061B2 · kind B2 · utility
67Cited by
7References
24Claims
0Family size
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Key dates
| Filing date | Dec 22, 2004 |
| Grant date | Aug 12, 2008 |
| Priority date | — |
| Expiry date | Aug 1, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of synthesizing polynucleotides is disclosed. The method involves contacting a first nucleotide with a selected reactive group in the presence of an ionic liquid. The selected reactive group may be on a second nucleotide, a polynucleotide, or on a moiety on an insoluble substrate, for example in an oligonucleotide synthesizer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.