Substrates and screening methods for transport proteins
US7413536B1 · kind B1 · utility
19Cited by
18References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 14, 2000 |
| Grant date | Aug 19, 2008 |
| Priority date | — |
| Expiry date | Sep 14, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A variety of methods for assaying libraries of test compounds as ligands and/or substrates of transport proteins, including both carrier-type and receptor-type transport proteins, are provided. Both in vitro and in vivo screening methods are disclosed. Also provided are methods for screening DNA libraries to identify members that encode transport proteins. Pharmaceutical compositions including compounds identified via the screening methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.