Sequential reaction system

US7413714B1 · kind B1 · utility

Assignee

• YMC CO., LTD. · KR

Inventors

• Thomas Schwalbe · Bad Vilbel, DE
• Klaus Golbig · Maintal, DE
• Michael Hohmann · Leipzig, DE
• Andreas Oberbeck · Wiesbaden, DE
• Shahriyar Taghavi-Moghadam · Neu-Isenburg, DE

Key dates

• Filing date: Jul 16, 2000
• Grant date: Aug 19, 2008
• Expiry date: Dec 3, 2022

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

An automated sequential reaction system that can be used to either sequentially produce a plurality of different products each requiring a single reaction, or to produce a desired product that requires a series of sequential reactions. A system controller controls an automated reactant supply, a solvent supply, a reaction module, a detector, and a product collector. Prior to initiating any reaction, the system is flushed with solvent and a heat exchanger supplies the reaction module with a temperature-conditioned fluid to maintain the reaction module at a desired temperature. For single reactions, a plurality of reactants are injected into a chemical reactor included in the reaction module. As fluid exits the chemical reactor, the detector determines if the fluid is a desired chemical product or solvent, and routes the fluid to the appropriate receptacle. Once a predetermined volume of a desired product is obtained, the system is flushed with solvent, and a different set of reactants are injected into the chemical reactor to produce the next desired product. The process is repeated until a substance library of the desired products is obtained. For products requiring sequential reac…