Uses of carbamoyl phosphate synthetase for the diagnois of inflammatory diseases and sepsis

US7413850B2 · kind B2 · utility

Assignee

• B.R.A.H.M.S GMBH · DE

Inventors

• Andreas Bergmann · Berlin, DE
• Joachim Struck · Berlin, DE
• Monika Uhlein · Berlin, DE

Key dates

• Filing date: Apr 15, 2003
• Grant date: Aug 19, 2008
• Expiry date: Jul 26, 2023

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/26
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Use of carbamoyl phosphate synthetase 1 (CPS 1) and/or of fragments of the N-terminal part of CPS 1 from body fluids or body tissues as marker peptides for the diagnosis and for the prognosis and the monitoring of inflammations and infections, including sepsis, and of liver failure as part of multiorgan failure or for determinations in connection with inflammatory and other liver diseases.