Nucleophosmin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
US7413851B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Dec 15, 2003 |
| Grant date | Aug 19, 2008 |
| Priority date | — |
| Expiry date | Aug 25, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6875
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are methods for detecting neoplastic or damaged cells and for detecting multidrug resistance in neoplastic or damaged cells by detecting an increase in the cell surface expression of a nucleophosmin (NPM) protein on the surface of such a multidrug resistant neoplastic or damaged cells as compared to the level of expression of the nucleophosmin protein on the surface of a normal cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.