Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
US7413866B2 · kind B2 · utility
0Cited by
15References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 2003 |
| Grant date | Aug 19, 2008 |
| Priority date | — |
| Expiry date | Apr 22, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for identifying an agent that specifically binds and/or modulates one topology of a chemokine receptor but not a second topology of the receptor. Such agents are useful as therapeutics for diseases or conditions associated with a particular chemokine receptor topology. Moreover, the agents are useful for detecting a particular topology of a chemokine receptor, thereby diagnosing disease or predisposition for a disease. In addition, the agents are useful for identifying and isolating cells that express a particular topology of a chemokine receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.