Method for the identification of antagonists of a phenylthiocarbamide/bitter taste receptor

US7413867B2 · kind B2 · utility

Assignee

• Deutsches Institut für Ernährungsforschung, Stiftung des öffentlichen Rechts, Vertreten durch den Stiftungsvorstand · DE

Inventors

• Bernd Bufe · Ferch, DE
• Thomas Hofmann · Doylestown, US
• Dietmar Krautwurst · Brüssow, DE
• Christina Kuhn · Michendorf, DE
• Wolfgang Meyerhof · Norderstedt, DE

Key dates

• Filing date: Sep 25, 2003
• Grant date: Aug 19, 2008
• Expiry date: Nov 10, 2023

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block bitter taste transduction, or enhance bitter taste response.