Ophthalmic compositions for treating ocular hypertension

US7414067B2 · kind B2 · utility

Assignees

• MERCK & CO., INC. · US
• Evotec OAI AG · DE

Inventors

• Edward Andrew Boyd · Biggenden, AU
• Michael H. Fisher · Bound Brook, US
• Maria L. Garcia · Edison, US
• Gregory J. Kaczorowski · Rahway, US
• Peter T. Meinke · New York, US
• William H. Parsons · Montgomery, US
• Stephen Price · Hertford, GB
• John Harry Alexander Stibbard · Biggenden, AU

Key dates

• Filing date: Mar 24, 2004
• Grant date: Aug 19, 2008
• Expiry date: May 30, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.