Patent · US Active

Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones

US7414137B2 · kind B2 · utility

1Cited by
5References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 22, 2007
Grant dateAug 19, 2008
Priority date
Expiry dateMar 22, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C319/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.