Polyamine compounds and compositions for use in conjunction with cancer therapy
US7414154B2 · kind B2 · utility
0Cited by
10References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 17, 2004 |
| Grant date | Aug 19, 2008 |
| Priority date | — |
| Expiry date | Apr 4, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/27
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more chemoprotective polyamines formulated for topical or local delivery to epithelial or mucosal cells are disclosed. Methods of administering the pharmaceutical preparations are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.