Nucleotide sequences for encoding of the lysR2-gene

US7416863B2 · kind B2 · utility

Assignee

• Degussa AG · DE

Inventors

• Bettina Moeckel · Goldkronach, DE
• Mike Farwick · Essen, DE
• Thomas Hermann · Bielefeld, DE
• Caroline Kreutzer · Melle, DE
• Walter Pfefferle · Bodenwerder, DE

Key dates

• Filing date: Jul 12, 2005
• Grant date: Aug 26, 2008
• Expiry date: Oct 6, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/34
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c),and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.