4-bromo-5-(2-chloro-benzoylamino)-1H-pyrazole-3-carboxylic acid amide derivatives and related compounds as bradykinin B1 receptor antagonists for the treatment of inflammatory diseases
US7417152B2 · kind B2 · utility
4Cited by
4References
11Claims
0Family size
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Key dates
| Filing date | Apr 30, 2004 |
| Grant date | Aug 26, 2008 |
| Priority date | — |
| Expiry date | Apr 30, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds of formula I and II that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.