Medical devices for delivering a therapeutic agent and method of preparation
US7419696B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 30, 2005 |
| Grant date | Sep 2, 2008 |
| Priority date | — |
| Expiry date | Dec 16, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/432
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.