Sequences encoding PhzO and methods

US7419812B2 · kind B2 · utility

Assignees

• The United States of America, as represented by the Secretary of Agriculture · US
• Washington State University Research Foundation · US

Inventors

• Linda S. Thomashow · Pullman, US
• Shannon M. Delaney · Schiller Park, US
• Dmitri V. Mavrodi · Hattiesburg, US
• David M. Weller · Pullman, US

Key dates

• Filing date: Mar 26, 2004
• Grant date: Sep 2, 2008
• Expiry date: Jun 9, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/0004
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Th invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.