Cell lines
US7419827B2 · kind B2 · utility
4Cited by
15References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 21, 2005 |
| Grant date | Sep 2, 2008 |
| Priority date | — |
| Expiry date | Nov 21, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Genomic instability in T-antigen expressing cells can be overcome by modifying the gene expressing T-antigen so that it lacks Bub1 binding. Stable cell lines can be produced by incorporation of the modified T-antigen gene, preferably together with the catalytic sub-unit of the telomerase construct.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.