Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors

US7419978B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Jagabandhu Das · Mercerville, US
• John Hynes · Washington Crossing, US
• Katerina Leftheris · Skillman, US
• Shuqun Lin · Newtown, US
• Stephen T. Wrobleski · Whitehouse Station, US
• Hong Wu · Meekrap-oord, CN

Key dates

• Filing date: Oct 21, 2004
• Grant date: Sep 2, 2008
• Expiry date: Oct 17, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the formula (I),and pharmaceutically acceptable salts, prodrugs, and solvates thereof, are useful as kinase inhibitors, wherein R, R1, R2, R5, R6a, R6b, J, K, X and Z are as described in the specification.