Neisseria meningitidis compounds and anti-infection applications thereof

US7422754B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Xavier Nassif · Paris, FR
• Colin Tinsley · Paris, FR
• Silke Klee · Berlin, DE
• Mark Achtman · Berlin, DE
• Petra Merker · Berlin, DE

Key dates

• Filing date: May 14, 2004
• Grant date: Sep 9, 2008
• Expiry date: May 28, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/505
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides novel Neisseria meningitides (Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also provided are anti-Nm infection, and particularly diagnostic. prophylactic and therapeutic uses thereof.