Feedback-resistant mevalonate kinases
US7422884B2 · kind B2 · utility
29Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2004 |
| Grant date | Sep 9, 2008 |
| Priority date | — |
| Expiry date | Sep 10, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to modified mevalonate kinases that are less sensitive to feedback inhibition, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing isoprenoid compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.