2-(3-Aminoaryl)amino-4-aryl-thiazoles for the treatment of diseases
US7423055B2 · kind B2 · utility
6Cited by
5References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 2003 |
| Grant date | Sep 9, 2008 |
| Priority date | — |
| Expiry date | Aug 1, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds selected from 2-(3-aminoaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.