Patent · US Expired

Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents

US7423057B2 · kind B2 · utility

7Cited by

1References

12Claims

0Family size

Assignee

4SC AG · DE

Inventors

Johan Leban · Birkenfeld, DE
Bernd Kramer · Aachen, DE
Wael Saeb · Gräfelfing, DE
Gabriel Garcia · Fullerton, US

Key dates

Filing date	Feb 17, 2006
Grant date	Sep 9, 2008
Priority date	—
Expiry date	Feb 17, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2601/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a novel compounds that can be used as anti-inflammatory, immunomodulatory and antiproliferatory agents. In particular, the invention refers to new compounds which inhibit dihydroorotate dehydrogenase (DHODH), a process for their manufacture, pharmaceutical compositions containing them and to their use for the treatment and prevention of diseases, in particular their use in diseases where there is an advantage in inhibiting dihydroorotate dehyrogenase (DHODH).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.