Surface-modified base matrices
US7423070B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 18, 2003 |
| Grant date | Sep 9, 2008 |
| Priority date | — |
| Expiry date | Aug 21, 2024 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/3804
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention is a surface-modified base matrix comprised of a porous polymeric base matrix onto which branched hydrophilic polyhydroxy-functional polymers have been covalently attached, wherein the polyhydroxy-functional polymers are hyperbranched polymers presenting a degree of branching (DB) of at least about 0.2 and each polymer is tethered to the base matrix at two or more points. The present matrix can for example be a cross-linked carbohydrate material, such as agarose, and the hyperbranched hydrophilic polymer can e.g. be a copolymer of epichiorohydrin and a sugar. The invention also relates to a method of surface-modification of a porous base matrix by activating functional hydroxy groups thereon and contacting the activated matrix with a hydrophilic hyperbranched hydroxy-functional polymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.