Patent · US Active

Amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compounds for the inhibition of β-secretase

US7423158B2 · kind B2 · utility

25Cited by
8References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 25, 2006
Grant dateSep 9, 2008
Priority date
Expiry dateSep 25, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula IThe present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.