FcγRIIB-specific antibodies and methods of use thereof
US7425620B2 · kind B2 · utility
63Cited by
15References
15Claims
0Family size
Inventors
Key dates
| Filing date | Aug 14, 2003 |
| Grant date | Sep 16, 2008 |
| Priority date | — |
| Expiry date | Dec 5, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/732
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.