Methods for determining renal toxins
US7426441B2 · kind B2 · utility
12Cited by
17References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 18, 2005 |
| Grant date | Sep 16, 2008 |
| Priority date | — |
| Expiry date | Oct 31, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S707/99948
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known renal toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.