N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl)-N-phenylamines as antiproliferative compounds
US7427627B2 · kind B2 · utility
2Cited by
1References
25Claims
0Family size
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Key dates
| Filing date | May 11, 2006 |
| Grant date | Sep 23, 2008 |
| Priority date | — |
| Expiry date | May 11, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.