Oral insulin therapy

US7429564B2 · kind B2 · utility

Assignee

• Emisphere Technologies, Inc. · US

Inventors

• Ehud Arbit · Englewood, US
• Richat Abbas · Potsdam, US
• Michael Goldberg · Englewood, US
• T. Woods · New York, US
• Steven Dinh · Burlington, US
• Vivien Wong · Kapar, MY

Key dates

• Filing date: Jan 7, 2003
• Grant date: Sep 30, 2008
• Expiry date: Dec 17, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical dosage forms for oral administration to a patient for the treatment of diabetes, comprising insulin and a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and that result in a lower incidence of vascular diseases associated with the repeated administration of insulin are disclosed. Also disclosed is a method of attenuating the undesirable incidence of diseases associated with chronic dosing of insulin is provided whereby the oral administration to a patient of insulin along with a suitable delivery agent that facilitates the absorption of insulin from the gastrointestinal tract of the patient in a therapeutically effective amount, for treatment of diabetes.