Tricyclic inhibitors of poly(ADP-ribose) polymerases
US7429578B2 · kind B2 · utility
9Cited by
17References
5Claims
0Family size
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Key dates
| Filing date | Sep 6, 2005 |
| Grant date | Sep 30, 2008 |
| Priority date | — |
| Expiry date | Jun 15, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula below are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease.As cancer therapeutics, the compounds of the invention may be used, e.g., in combination with cytotoxic agents and/or radiation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.