C-fms kinase inhibitors

US7429603B2 · kind B2 · utility

Assignee

• 3-Dimensional Pharmaceuticals, Inc. · US

Inventors

• Mark R. Player · Phoenixville, US
• Nand Baindur · Kendall Park, US
• Benjamin Brandt · Philadelphia, US
• Naresh Chadha · Nutley, US
• Raymond J. Patch · Yardley, US
• Davoud Asgari · Wilmington, US
• Taxiarchis Georgiadis · Carmel, US

Key dates

• Filing date: Apr 26, 2004
• Grant date: Sep 30, 2008
• Expiry date: Aug 25, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to compounds of Formulae I, II and III:wherein A, R1, R2, R3, R4, X, Y and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.